Combination Chemotherapy to Hodgkin's Disease in a Pregnant Patient.
- Author:
Eun Kee SONG
1
;
Jae Yong KWAK
;
Seung Ok LEE
;
Chang Yeol YIM
Author Information
1. Department of Internal Medicine, Chonbuk National University, Medical School, Chonju, Korea. jykwak@moak.chonbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Hodgkin's disease;
Pregnancy;
ABVD
- MeSH:
Bleomycin;
Drug Therapy, Combination*;
Female;
Fetus;
Hodgkin Disease*;
Humans;
Pregnancy;
Pregnant Women;
Recurrence;
Vinblastine
- From:Korean Journal of Hematology
2002;37(4):307-311
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Coincident Hodgkin's disease and pregnancy is rare and optimal management requires special consideration because usual treatment modalities are associated with significant risk to the developing fetus. We have experienced a 20 weeks pregnant woman with Hodgkin's disease. Combination chemotherapy with ABV (Adriamycin, Bleomycin, Vinblastine) 3 cycles were given during 2nd and 3rd trimester. She was delivered of a baby the 40 weeks of pregnancy without any problem. After delivery, she received additional 3 cycles of combination chemotherapy with ABVD (Adriamycin, Bleomycin, Vinblastine, Dacarbazine). Then, radiation treatment with Mantle technique, total 3,600cGy was performed. Finally, she reached the complete remission. After 12 months from the end of treatment, there was no evidence of recurrence and the baby are developing without any anomaly.
