A Case of Recurrent Subacute Necrotizing Lymphadenitis with Pancytopenia.
- Author:
Bo Kwon HWANG
1
;
Jin Seok JEON
;
Jae Ho BYUN
;
Gyu Taeg LEE
;
Jin Woo JEON
;
Sung Gyu PARK
;
Jong Ho WON
;
Seung Ho BAICK
;
Dae Sik HONG
;
Hee Sook PARK
Author Information
1. Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Subacute necrotizing lymphadenitis;
Kikuchi disease;
Pancytopenia
- MeSH:
Abdominal Pain;
Biopsy;
Blood Platelets;
Bone Marrow;
Fever;
Hematocrit;
Histiocytes;
Histiocytic Necrotizing Lymphadenitis;
Hyperplasia;
Laparotomy;
Lymph Nodes;
Lymphadenitis*;
Megakaryocytes;
Pancytopenia*;
Peritoneal Cavity;
Tomography, X-Ray Computed
- From:Korean Journal of Hematology
1997;32(2):318-323
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of recurrent subacute necrotizing lymphadenitis with pancytopenia in 21-years-old-woman. She was admitted to our hospital 4-years interval with fever and abdominal pain. Laboratory findings of the last admission showed pancytopenia, such as WBC 700/microliter, hemoglobin 6.0mmol/L (9.7g/dL), hematocrit 28.8%, and platelet 54,000/microliter. Abdominal CT showed hepatosplenomegaly, enlarged conglomerated lymph nodes in splenic hilum, lesser sac, celiac root, and paraaortic areas. Bone marrow biopsy showed hypocellular marrow (20%) with increased number of megakaryocyte, myeloid hyperplasia, and hemophagocytic histiocytes suggesting infectious process. We performed exploratory laparotomy, and pathologic finding revealed subacute necrotizing lymphadenitis-Kikuchi disease-. She was recovered on 26th hospital day with conservative treatment.
