A Case of Cyclic Hematopoiesis.
- Author:
Sang Mi OH
1
;
Hyoung Sik KIM
;
Jae Yong KWAK
;
Chang Yeol YIM
Author Information
1. Department of Internal Medicine, Chonbuk National University Medical School, Chonju, Korea.
- Publication Type:Case Report
- Keywords:
Cyclic hematopoiesis;
Cyclic neutropenia;
rhG-CSF
- MeSH:
Adolescent;
Biopsy;
Blood Cells;
Bone Marrow;
Hematopoiesis*;
Humans;
Male;
Neutropenia;
Pancytopenia
- From:Korean Journal of Hematology
1997;32(3):428-432
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Classical cyclic neutropenia is the most frequent of the cyclic hematopoietic disorders and a rare condition characterized by regular and predictable oscillations in the peripheral neutophil counts with the cycle length varying from 14 to 28 days and in many cases simultaneous fluctuation in the other blood cell line. The etiology of cyclic neutropenia is unknown, but has usually been considered as stem-cell disorder. We have observed a 17-year-old boy with a cyclic pancytopenia with a constant and predictable oscillation period of about 120 days. Serial bone marrow biopsies showed a similar fluctuating pattern and myelodysplatic change. We report this case and review the literature regarding this unusal long period cyclic neutropenia.
