A Case of Pure Red Cell Aplasia Associated with Sinus Histiocytosis with Multiple Lymphadenopathy.
- Author:
Jae Hyuk CHUNG
1
;
Young Bae SEO
;
Jong Hyun CHOI
;
Sang Min PARK
;
Ki Young CHOI
;
Kyung Chun KIM
;
Hyo Kun BAE
;
Soon YI
;
Jae Won YIM
Author Information
1. Department of Internal Medicine, Pohang Sunlin Hospital, Han Dong University, Pohang, Korea.
- Publication Type:Case Report
- Keywords:
Pure red cell aplasia;
Sinus histiocytosis;
Epstein-Barr virus
- MeSH:
Anemia;
Biopsy;
Bone Marrow;
Erythroblasts;
Herpesvirus 4, Human;
Histiocytes;
Histiocytosis, Sinus*;
Lymph Nodes;
Lymphatic Diseases*;
Lymphocytes;
Red-Cell Aplasia, Pure*
- From:Korean Journal of Hematology
2000;35(3-4):279-283
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pure red cell aplasia (PRCA) is characterized by severe anemia with reticulocytopenia and absence of erythroblast from the bone marrow. Sinus histiocytosis with massive lymphadenopathy (SHML : Rosai-Dorfman disease) is rare systemic disease characterized by painless cervical, axillary, inguinal and mediastinal lymphadenopathy and frequent extranodal invasion. Histologically, lymph node sinuses are expanded by numerous distinctive histiocytes which contains well preserved lymphocytes. We report a case of sinus histiocytosis with massive lymphadenopathy in inguinal lymph node biopsy with polyclonal gammopathy and pure red cell aplasia in bone marrow biopsy who was infected by Epstein-Barr virus.
