A Case of Colonic Perforation associated with CMV Colitis in a Patient with Non-Hodgkin's Lymphoma.
- Author:
Seung Hyeok HAN
1
;
Jee Sook HAHN
;
Seung Tae LEE
;
Joon Ho JANG
;
Yoo Hong MIN
;
Yun Woong KO
;
Nam Kyu KIM
;
Hoguen KIM
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Non-Hodgkin's lymphoma;
CMV colitis;
Perforation
- MeSH:
Colitis*;
Colon*;
Cytomegalovirus;
Early Diagnosis;
Ganciclovir;
Gastrointestinal Tract;
Hemorrhage;
Humans;
Ileum;
Immunocompromised Host;
Intestinal Perforation;
Lymphoma, Non-Hodgkin*;
Polymerase Chain Reaction;
Ulcer
- From:Korean Journal of Hematology
1999;34(4):619-624
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus (CMV) disease in gastrointestinal tract is common among immunocompromised host. Ulcer, hemorrhage and perforation are manifestations of CMV infection in gastrointestinal tract and the most common site of intestinal perforation is the colon, followed by the distal ileum. Early diagnosis and preemptive therapy of CMV infection in the gastrointestinal tract should be warranted to prevent intestinal perforation, one of life-threatening complications of CMV colitis. We report a case of CMV colitis leading to colonic perforation in a patient with non-Hodgkin's lymphoma (T/NK cell lymphoma). Immunohistochemical stain of surgical specimen revealed positive, followed by positive EA-IPA and PCR for CMV antigen. He survived after successful left hemicolectomy and intravenous ganciclovir therapy.
