A Case of Multiple Myeloma Presented with a Bulky Cranial Plasmacytoma Invading Cerebrum.
- Author:
Pum Joon KIM
1
;
Ji Youn HAN
;
Tae Gyun KIM
;
Jae Gen AHN
;
Kang Hoon LEE
;
Hyeon Sook KIM
;
Chul JI
;
Kyung Shick LEE
Author Information
1. Depatment of Internal Medicine, College of Medicine, The Catholic Universiy of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Multiple myeloma;
Cranial plasmacytoma
- MeSH:
Cerebrum*;
Drug Therapy;
Dura Mater;
Humans;
Lower Extremity;
Mucous Membrane;
Multiple Myeloma*;
Plasmacytoma*;
Prognosis
- From:Korean Journal of Hematology
1999;34(3):477-481
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Although neurologic complications of multiple myeloma are common, brain-involvement is rare, despite the high frequency of the cranial lesions. The cranial plasmacytoma grows only from bone, dura mater or adjacent mucous membrane and cerebral structures are affected secondarily. It is less likely that a solitary cranial plasmacytoma exists, and patients who harbor these neoplasms should undergo complete evaluations to exclude multiple myeloma. Solitary plasmacytoma is radiosensitive and the definite treatment for the cranial plasmacytoma usually consists of complete surgical resection with adjacent radiation therapy. However, the treatment and prognosis of the cranial plasmacytoma depends on whether this neoplasm is primary or secondary. Most of patients develop cranial plasmacytoma as the presenting form of multiple myeloma and the treamtment of in these speical cases is usually unsatisfatory. We report a case of multiple myeloma presented with the motor weakness of both upper and lower extremities by a bulky cranial plasmacytoma invading cerebrum treated with surgery, radiation therapy and chemotherapy.
