A Case of Angiocentric T Cell Lymphoma Accompanied with Multiple Erythematous Nodules, Subcutaneous Mass on the Right Face and Peripheral Polyneuropathy.
- Author:
Hyung Wook KIM
1
;
Suk Young PARK
Author Information
1. Department of Internal Medicine, Deajon St. Mary's Hospital, College of Medicine, Catholic University.
- Publication Type:Case Report
- Keywords:
Angiocentric T cell lymphoma;
Atypical lymphoid cell;
Combination chemotherapy
- MeSH:
Drug Therapy, Combination;
Female;
Humans;
Lymphocytes;
Lymphoma, T-Cell*;
Lymphoma, T-Cell, Peripheral;
Polyneuropathies*;
Skin;
Vincristine
- From:Korean Journal of Hematology
1997;32(1):140-145
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Angiocentric T cell lymphoma is a variant of peripheral T cell lymphoma characterized by an angiocentric and angioinvasive infiltrates, invasion of vascular walls, and occulsion of lumen by atypical lymphoid cells with varying degrees of cytologic atypia. We recently experienced a woman with angiocentric T cell lymphorma, who presented with multiple erythematous nodules of skin, subcutaneous mass on right face and peripheral polyneuropathy. At the skin biopy specimen, we could find angiocentric and angioinvasive infiltrate by atypical lymphoid cells which showed a positive immunohistochemical reaction for CD45RO that is one of the T cell markers and a negative reaction for B cell marker. She was treated with two cycles of combination chemotherapy composed of CVP (cyclophosphamide, vincristine, prednisolone), that resulted in complete remission.
