A Case of AILD-like T Cell Lymphoma with Monoclonal Gammopathy.
- Author:
Byoung Hun KIM
1
;
Myung Ju AHN
;
Joo Hyun SON
;
Young Youl LEE
;
Tae Jun JUNG
;
In Soon KIM
;
Il Young CHOI
;
Ile Kyu PARK
;
Se Jin JANG
;
Yong Wook PARK
;
Joong Dal LEE
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
AILD-like T cell lymphoma;
Monoclonal gammopathy
- MeSH:
Aged;
Amyloidosis;
Biopsy;
Bone Marrow;
Cyclophosphamide;
Doxorubicin;
Drug Therapy, Combination;
Humans;
Immunoblastic Lymphadenopathy;
Immunohistochemistry;
Lymph Nodes;
Lymphatic Diseases;
Lymphocytes;
Lymphoma, T-Cell*;
Paraproteinemias*;
Prednisone;
T-Lymphocytes;
Vincristine
- From:Korean Journal of Hematology
1997;32(1):146-151
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of 74 year old man presented with generalized lymphadenopathy with hepatosplenomegaly. Lymph node biopsy revealed angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) and most areas of lymph node were replaced with large atypical lymphocytes which were revealed to be T cells by immunohistochemistry. All together, the patient was diagnosed as AILD-like T cell lymphoma with bone marrow involvement. The patient presented monoclonal gammopathy (IgG lambda) without any evidence of plasma cell dyscrasia or secondary amyloidosis. After three cycles of combination chemotherapy including cyclophosphamide, prednisone, vincristine and doxorubicin, the patient achieved partial remission with decreased level of serum and urine monoclonal protein.
