Two Cases of Intravascular Lymphomatosis.
- Author:
Soon IL LEE
1
;
Won Seog KIM
;
Jeeyun LEE
;
Seo Young SONG
;
Joon Oh PARK
;
Kihyun KIM
;
Chul Won JUNG
;
Young Hyuck IM
;
Won Ki KANG
;
Hong Ghi LEE
;
O Jung KWON
;
Ki Woong SUNG
;
Hong Hoe KOO
;
Young hyeh KO
;
Sung Soo YOON
;
Keunchil PARK
Author Information
1. Department of Internal Medicine, Samsung Medical Center, College of Medicine, Sungkyunkwan University, Korea. wskimsmc@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Intravascular lymphomatosis;
Skin rash;
Fever;
Combination chemotherapy
- MeSH:
Biopsy;
Blood Vessels;
Central Nervous System;
Dementia;
Diagnosis;
Drug Therapy, Combination;
Dyspnea;
Exanthema;
Fever;
Lymphoma;
Skin;
Stroke;
Vasculitis
- From:Korean Journal of Hematology
2002;37(2):138-142
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intravascular lymphomatosis is a rare lymphoma characterized by neoplastic proliferation of malignant cells within the lumen of small blood vessels, usually presenting in the central nervous system or on the skin. Intravascular lymphomatosis is manifested clinically by fever, dementia, cutaneous nodules or plaques, and occasionally, dyspnea. The diagnosis of intravascular lymphomatosis is difficult because of misleading clinical features mimiking vasculitis, infection, stroke, or other neoplasm. We report two cases of intravascular lymphomatosis pesented as fever and skin rash. Those are confirmed by involved tissue biopsy. All cases were treated by combination chemotherapy, but the response was not good. Infectious problems were complicated and disease were progressed.