A Case with Plasma Cell Leukemia and Anaplastic Large T cell Lymphoma.
- Author:
Ji Myung KIM
1
;
Chan Jeoung PARK
;
Joo Ryung HUH
;
Yoon Ku KANG
;
Hyun Sook CHI
Author Information
1. Department of Clinical Pathology, University of Ulsan College of Medicine and Asan Medical center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Plasma cell leukemia;
Anaplastic large T-cell lymphoma
- MeSH:
B-Lymphocytes;
Biopsy;
Bone Marrow;
Dyspepsia;
Electrophoresis;
Immunoglobulin G;
Leukemia, Plasma Cell*;
Lymphoma, T-Cell*;
Paraproteinemias;
Plasma Cells*;
Plasma*;
Pleural Effusion;
Stomach;
T-Lymphocytes
- From:Korean Journal of Hematology
2001;36(2):162-166
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The association of B-cell and T-cell disorders is rare. We report a case with coexisting plasma cell leukemia and anaplastic large T cell lymphoma. It is believed to be the first case reported in the literature. A 49-year man was admitted to the hospital because of indigestion. On the gastrofibroscopic examination, a huge, ulcerofungating mass was detected in the stomach, and Ki-1 positive anaplastic large T-cell lymphoma was diagnosed on the biopsy. On the peripheral blood smear and bone marrow study performed as a part of the staging work-up, plasma cell leukemia was diagnosed. The protein electrophoresis and immunofixation of serum and urine revealed IgG, lamda type monoclonal gammopathy. But in the pleural effusion, the involvement of anaplastic large T-cell lymphoma was noted.