A Case of Lymphomatoid Papulosis after Allogenic Bone Marrow Transplatation.
10.5045/kjh.2005.40.2.111
- Author:
Jae Myoung CHOI
1
;
Hyun Woo LEE
;
Seok Yun KANG
;
Jun Ho JANG
;
Joon Seong PARK
;
Jin Hyuk CHOI
;
Ho yeong LIM
;
Hugh Chul KIM
;
Eun So LEE
Author Information
1. Department of Hematology-Oncology, Ajou University School of Medicine, Suwon, Korea. hughkim@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
GVHD;
Lymphomatoid papulosis;
Bone marrow transplantation
- MeSH:
Bone Marrow Transplantation;
Bone Marrow*;
Cicatrix;
Eosinophils;
Erythrocytes;
Extremities;
Fibrin;
Forearm;
Humans;
Lymphocytes;
Lymphomatoid Papulosis*;
Neutrophils;
Skin;
Tissue Donors
- From:Korean Journal of Hematology
2005;40(2):111-115
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A twenty-year-old man developed pruritic papules on his right forearm on the 25th day after an allogeneic bone marrow transplantation from an HLA-matched related donor. The skin lesion turned out to be lymphomatoid papulosis, both histologically and immunophenotypically, not a GVHD skin lesion. Lymphomatoid papulosis is a chronic lymphoproliferative disease of the skin, characterized by recurrent crusts of pruritic papules, which initially appearing on the upper trunk and both extremities. The lesions heal spontaneously within 2~8 weeks, usually leaving slightly depressed oval scars. Histologically, the lesions show wedge-shaped dense dermal infiltrates of lymphoid cells, with numerous eosinophils, neutrophils and atypical lymphocytes. As much as 50% of the infiltrates show atypical lymphocytes, and the dermal vessels may show endothelial swelling, fibrin deposition and red blood cell extravasation. We are reporting a case of spontaneously healing CD56+ lymphomatoid papulosis, in the patient who received bone marrow transplantation, is reported.
