A Case of Small Cell Variant of T-Cell Prolymphocytic Leukemia.
10.5045/kjh.2005.40.3.177
- Author:
Jee Eun PARK
1
;
Kwang Min KIM
;
Woo Youl KIM
;
Yong Hwan PARK
;
Ji Eun OH
;
Young Jae KIM
;
Kyung Tae PARK
Author Information
1. Department of Internal Medicine, Masan Samsung Hospital, Sungkyunkwan University School of Medicine, Masan, Korea.
- Publication Type:Case Report
- Keywords:
T-cell prolymphocytic leukemia;
Small cell variant
- MeSH:
Leukemia, Prolymphocytic, T-Cell*;
Lymphatic Diseases;
Lymphocytosis;
Skin;
T-Lymphocytes*
- From:Korean Journal of Hematology
2005;40(3):177-182
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
T-cell prolymphocytic leukemia (T-PLL) is a post-thymic T-cell malignancy that has an aggressive clinical course and it is a distinct clinico-biological entity from other T-cell disorders. It is now apparent that this disease represents a separate entity from CLL. Clinically, T-PLL presents with hepatosplenomegaly, lymphadenopathy, skin lesion, and marked lymphocytosis exceeding 100x109/L. Because its clinical course is aggressive, the treatment is difficult. We report a case of small cell variant of T-cell with a review of literatures.