A Case of Acquired Glanzmann's Thrombasthenia.
10.5045/kjh.2005.40.3.183
- Author:
So Yeon OH
1
;
Moon Ju JANG
;
Myung Seo KANG
;
Doyeun OH
;
So Young CHONG
Author Information
1. Department of Internal Medicine, Pochon CHA University College of Medicine, Seongnam, Korea. sychong@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Acquired thrombasthenia;
Evans' syndrome;
Platelet aggregation
- MeSH:
Antibodies;
Blood Platelets;
Hemorrhage;
Humans;
Membrane Glycoproteins;
Platelet Aggregation;
Platelet Count;
Thrombasthenia*
- From:Korean Journal of Hematology
2005;40(3):183-187
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Glanzmann's thrombasthenia (GT) is a rare inherited platelet disorder, which is characterized by a complete lack of platelet aggregation due to a deficiency or abnormality of the membrane glycoprotein IIb/IIIa complex. Anti-GPIIb/IIIa antibodies have also been identified to cause platelet dysfunction in patients with a normal platelet count, but this has only been rarely encountered. The condition is also known as acquired GT. Herein, we describe a patient with acquired GT and a history of Evans' syndrome, who presented with severe bleeding and platelet dysfunction, but with a normal platelet count and GP IIb/IIIa expression.
