A Case of Myeloid Blast Crisis of Atypical Chronic Myelogenous Leukemia.
- Author:
Hee Soon CHO
1
;
Chae Hoon LEE
;
Kyung Dong KIM
;
Kyung Hee LEE
;
Sung Hwa BAE
;
Duck CHO
;
Dong Wook RYANG
Author Information
1. Department of Laboratory Medicine, Yeungnam University College of Medicine, Daegu, Korea. chscp@hanmail.net
- Publication Type:Case Report
- Keywords:
Atypical chronic myelogenous leukemia;
Myeloid blast crisis;
Monosomy 7;
Deletion of 12p
- MeSH:
Blast Crisis*;
Cytogenetics;
Humans;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive*;
Monosomy
- From:Korean Journal of Hematology
2003;38(3):200-204
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Atypical chronic myelogenous leukemia (aCML) has dysplastic as well as proliferative features in most instance and rarely evolves to blast crisis, so it is considered as a distinct clinical entity to classical BCR-ABL (+) CML. We experienced a patient who are diagnosed aCML and transformed to myeloid blast crisis after 17 months. Monosomy 7 and deletion of 12p were found on conventional cytogenetics.
