A Case of Blastic Mantle Cell Leukemia.
- Author:
Hee Jin HUH
1
;
Chan Jeoung PARK
;
Soo Jin YOO
;
Seongsoo JANG
;
Hyun Sook CHI
;
Kyoo Hyung LEE
Author Information
1. Department of Laboratory Medicine, College of Medicine, University of Ulsan and Asan Medical Center, Seoul, Korea. cjpark@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Blastic mantle cell leukemia;
Cyclin D1
- MeSH:
Bone Marrow;
Chromatin;
Cyclin D1;
Cytoplasm;
Immunophenotyping;
Leukemia*;
Lymphocytes;
Lymphoma, Mantle-Cell;
Precursor Cell Lymphoblastic Leukemia-Lymphoma
- From:Korean Journal of Hematology
2004;39(4):257-261
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The Word Health Organization defines Mantle cell lymphoma (MCL), comprising two main morphological variant, blastoid and other variant. The classic type of blastoid variant show proliferation of lymphocytes, resembling lymphoblasts, with scant cytoplasm, rounded nuclei with fine dispersed chromatin and inconspicuous nucleoli. The blastoid variant is virtually indistinguishable from acute lymphoblastic leukemia based on blood and bone marrow morphology. We report one case of blastic mantle cell leukemia diagnosed by the immunophenotyping results and the detection of cyclin D1 overexpression on immunohistochemical stain.
