A Case of Epstein-Barr Virus Infection Presented as Evans Syndrome.
- Author:
Dong Woo HYUN
1
;
Dong Hwan KIM
;
Jin Tae JUNG
;
Sang Kyun SOHN
;
Jaetae LEE
;
Kyu Boo LEE
Author Information
1. Department of Internal Medicine, Kyungpook National University, School of Medicine, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
Evans syndrome;
Epstein-Barr virus
- MeSH:
Anemia, Hemolytic, Autoimmune;
Capsid;
Cytomegalovirus;
Fever;
Herpesvirus 4, Human*;
Immunoglobulin M;
Leukocytosis;
Lymphatic Diseases;
Lymphocytosis;
Pharyngitis;
Purpura, Thrombocytopenic, Idiopathic;
Thrombocytopenia
- From:Korean Journal of Hematology
1998;33(3):438-442
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Evans syndrome refer to autoimmune hemolytic anemia accompanied by thrombocytopenia. The etiologic factors of Evans syndrome are unknown but viral infections such as Epstein-Barr virus and cytomegalovirus are suggested. Epstein-Barr virus (EBV) infection is an acute illness characterized clinically by fever, sore throat, and lymphadenopathy; serologically by the transient positive heterophil antibody; and hematologically by mononuclear leukocytosis with atypical lymphocytosis. We experienced a case of Epstein-Barr virus infection presented as Evans syndrome. Epstein-Barr virus infection was diagnosed by positive heterophil antibody and EBV viral capsid antigen IgM. Autoimmune hemolytic anemia and immune thrombocytopenic purpura were completely resolved by steroid therapy.
