A Case of Non-secretory Plasma Cell Leukemia with Complex Chromosomal Abnormalities.
- Author:
Kyung A LEE
1
;
Oh Gun KWON
;
Ki Jin OH
;
Kap Jun YOON
;
Jong In LEE
Author Information
1. Department of Clinical Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea.
- Publication Type:Case Report
- Keywords:
Non-secretory plasma cell leukemia;
chromosomal abnormalities;
t (11;
14)(q13;
q32)
- MeSH:
Anemia;
Bone Marrow Examination;
Chromosome Aberrations*;
Cytogenetic Analysis;
Electrophoresis;
Humans;
Leukemia, Plasma Cell*;
Middle Aged;
Paraproteinemias;
Paraproteins;
Plasma Cells*;
Plasma*;
Renal Insufficiency;
Respiratory Distress Syndrome, Adult;
Thrombocytopenia
- From:Korean Journal of Hematology
1998;33(3):449-453
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of non-secretory plasma cell leukemia with complex chromosomal abnormalities including t (11;14)(q13;q32). A 57-year-old man was admitted to hospital due to anemia, thrombocytopenia and renal insufficiency. Bone marrow examination and peripheral blood smear revealed a large number of immature plasma cells with positivity for CD38. Monoclonal gammopathy or abnormal paraproteins were not observed in serum protein electrophoresis and immunofixation. The cytogenetic analysis showed complex chromosomal abnormalities [45, XY, -1, t (11;14)(q13;q32), t (12;17)(p13;q21)]. He was died of adult respiratory distress syndrome on the 6th hospital day.
