A Case of Hereditary Factor VII Deficiency Performed Operation without any Replacement Therapy.
- Author:
Hyung Mo OH
1
;
Nam Cheol WHANG
;
Soo Jin LIM
;
Joon Hyung KIM
;
Yun Kwon KIM
;
So Yon KIM
;
Young Jung KIM
;
Min Koo CHO
;
Gwon Jun LEE
Author Information
1. Department of Internal Medicine, National Police Hospital, Seoul, Korea. drsykim@chollian.net
- Publication Type:Case Report
- Keywords:
Hereditary factor VII deficiency;
Replacement therapy
- MeSH:
Epistaxis;
Factor VII Deficiency*;
Factor VII*;
Hemorrhage;
Herniorrhaphy;
Humans;
Parents;
Plasma;
Prothrombin;
Siblings;
Young Adult
- From:Korean Journal of Hematology
2001;36(4):351-354
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hereditary factor VII deficiency is a rare disorder transmitted by autosomal recessive pattern and its clinical feature is extremely variable. Recently we have experienced a case who was performed herniorrhaphy without any cryoprecipitate or fresh frozen plasma replacement therapy. A 21-year-old patient who had undergone intermittent nasal bleeding was noted for prolonged prothrombin time(INR of 1.5). The level of the factor VII of the patient was decreased at 22% of the normal activity. His parents had normal level of factor VII activity. Both his sister and brother had decreased level of factor VII at 41% and 24% respectively. Herniorrhaphy was performed without factor replacement therapy and there was no visible postoperative bleeding. We report here a case of factor VII deficiency performed an operation successfully without any replacement therapy.
