Trend of Clinicopathologic Characteristics of Colorectal Cancer in Asan Medical Center: a 15-Year Experience.
- Author:
Pyong Wha CHOI
1
;
Sang Hun JUNG
;
Jung Rang KIM
;
Chang Sik YU
;
Hee Cheol KIM
;
Jin Cheon KIM
Author Information
1. Colorectal Clinic, Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. jckim@www.amc.seoul.kr
- Publication Type:Multicenter Study ; Original Article
- Keywords:
Colorectal cancer;
Trend;
Stage
- MeSH:
Chungcheongnam-do*;
Colorectal Neoplasms*;
Demography;
Humans;
Korea;
Male;
Retrospective Studies
- From:Journal of the Korean Society of Coloproctology
2006;22(6):387-395
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: A retrospective study was performed to provide an overview of changes over time by age, stage, tumor location, and surgical therapy of colorectal cancer over the past 15 years. METHODS: We analyzed the cases 6,314 colorectal cancer patients who underwent surgery at Asan Medical Center between January 1990 and December 2004. The period was divided into three periods: 1990 to 1994, 1995 to 1999, and 2000 to 2004. We analyzed trends over time for stage, resectability, and demographic factors of colorectal cancer over the past 15 years. RESULTS: The mean age of the patients in the periods from 1990 to 1994, from 1995 to 1999, and from 2000 to 2004 were 57.1 (21~89), 57.4 (14~91), and 58.9 (15~91) years, respectively, showing an increasing tendency over time (P<0.001). The male-to-female ratios were 1.2 : 1, 1.3 : 1, and 1.6 : 1, repectively, and this male preponderance has been more marked in recent years (P=0.003). There was no change in tumor location over time. The ratios of early cancer to advanced cancer were 0.06 : 1, 0.09 : 1, and 0.11 : 1, respecfively, showing an increasing tendency over time (P=0.002). The curative resection rate increased over time (P<0.001). The non-curative resection rate was higher and the non-resected rate was lower in the period 2000 to 2004 than in the period 1990 to 1999 (P<0.001). The ratios of the lowest anterior resection to the abdominoperineal resection were 0.06 : 1, 0.49 : 1, and 1.02 : 1, respectively. With decreasing tendency of abdominoperineal resection, the lowest anterior resection rate has increased gradually over time (P<0.001). CONCLUSIONS: Etiologic studies are necessary to understand the male preponderance in colorectal cancer, and multi-center studies should be conducted to understand the changing trend of colorectal cancer in Korea.
