A Case of Benign Intracranial Hypertension (Pseudotumor cerebri) Associated with Systemic Lupus Erythematosus.
- Author:
Heok Soo AHN
1
;
Cheol Su LIM
;
Seung Ok LEE
;
Jae Yong KWAK
;
Chang Yeol YIM
Author Information
1. Department of Internal Medicine, Chonbuk Natioal University Medical School, Chonju, Korea.
- Publication Type:Case Report
- Keywords:
Systemic Lupus Erythematosus (SLE);
Benign Intracranial Hypertension (BIH)
- MeSH:
Absorption;
Antigen-Antibody Complex;
Arachnoid;
Brain;
Cerebrospinal Fluid;
Diagnosis;
Diuretics, Osmotic;
Female;
Humans;
Hydrocephalus;
Intracranial Pressure;
Lupus Erythematosus, Systemic*;
Pseudotumor Cerebri*;
Purpura, Thrombocytopenic, Idiopathic
- From:Korean Journal of Hematology
1999;34(1):131-136
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Benign intracranial hypertension (BIH) is very rare and its cause is unclear. Raised intracranial pressure in the absence of an intracranial mass or hydrocephalus (BIH or pseudotumor cerebri) has been described in association with many conditions including SLE. Several pathogenic pathways tie BIH with SLE as thrombotic obliteration of cerebral arteriolar and venous systems and immune complex deposition within the arachnoid villi that are responsible for cerebrospinal fluid (CSF) absorption. The diagnosis of BIH was confirmed by increased intracranial pressure in the absence of any abnormal radiological findings of the brain. We report a young woman with SLE and autoimmune thrombocytopenia complicated by BIH which resolved with corticosteroid therapy and osmotic diuretics.
