T-Cell Lymphoma with Rosai-Dorfman Syndrome-Like Feature.
- Author:
Dong Hoon KO
1
;
Jong Youl JIN
;
Yeun Shik KIM
;
Hyung Jun KIM
;
Hyun Jung JOO
;
Hong Gi KIM
;
Jeana KIM
;
Ji Min KAHNG
Author Information
1. Department of Internal Medicine, Holy Family Hospital, The Catholic University of Korea, College Of Medicine, Puchun, Korea.
- Publication Type:Case Report
- Keywords:
Rosai-Dorfman Syndrome;
T-cell lymphoma
- MeSH:
Anemia, Hemolytic;
Biopsy;
Doxorubicin;
Drug Therapy;
Female;
Fibrosis;
Histiocytosis, Sinus;
Humans;
Lymph Nodes;
Lymphatic Diseases;
Lymphoma, T-Cell*;
T-Lymphocytes*;
Vincristine
- From:Korean Journal of Hematology
1999;34(1):153-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
T-cell lymphoma is heterogeneous with respect to clinical presentation, course, and morphology, but it is rarely associated with sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman Syndrome). We report a case of T-cell lymphoma with Rosai-Dorfman Syndrome like feature in a 31-years-old woman who presented severe non-immune hemolytic anemia and massive retroperitoneal and cervical lymphadenopathy. Her cervical lymph node biopsy revealed histiocytic infiltration showing erythrophagocytosis without marked fibrosis in the capsular and pericapsular areas and distension of sinusoids. After 6 cycles of CHOP (Cyclophosphamide, Adriamycin, Vincristine, and Prednisolone) chemotherapy, cervical and retroperitoneal lymphadenopathy was completely disappeared and according to the resolution of lymphadenopathy hemolytic anemia was also improved.
