A Case of Hyperhomocysteinemia Manifested by Deep Vein Thrombosis and Pulmonary Embolism.
10.5045/kjh.2006.41.2.110
- Author:
Sung Ho LEE
1
;
Se Ho CHOI
;
Jong Hyun LEE
;
Kyoung Youn SEON
;
Shin Bae JOO
Author Information
1. Department of Internal Medicine, National Medical Center, Seoul, Korea. sbjookr@nate.com
- Publication Type:Case Report
- Keywords:
Pulmonary embolism;
Deep vein thrombosis;
Hyperhomocysteinemia
- MeSH:
Atherosclerosis;
Endothelial Cells;
Heredity;
Homocysteine;
Humans;
Hyperhomocysteinemia*;
Platelet Activation;
Pulmonary Embolism*;
Risk Factors;
Thrombosis;
Venous Thrombosis*
- From:Korean Journal of Hematology
2006;41(2):110-114
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Homocysteine has been reported as an independent risk factor of intravascular thrombosis and atherosclerosis by its participation in vascular endothelial cell dysfunction, platelet activation and thrombus formation. The serum homocysteine concentration is influenced by not only heredity, but also by environmental factors, and it interacts with the former reported risk factors of atherosclerosis. We report here on a case of a young patient with hyperhomocysteinemia that manifested by deep vein thrombosis and pulmonary embolism.