Comparison of Helical TomoTherapy with Linear Accelerator Base Intensity-modulated Radiotherapy for Head & Neck Cases.
- Author:
Dongwook KIM
1
;
Myonggeun YOON
;
Sung Yong PARK
;
Se Byeong LEE
;
Dong Ho SHIN
;
Doohyeon LEE
;
Jungwon KWAK
;
Soah PARK
;
Young Kyung LIM
;
Jinsung KIM
;
Jungwook SHIN
;
Kwan Ho CHO
Author Information
1. Proton Therapy Center, National Cancer Center, Goyang, Korea. cool_park@ncc.re.kr
- Publication Type:Original Article
- Keywords:
IMRT;
TomoTherapy;
Homogeneity;
IGRT;
NTCP
- MeSH:
Head;
Humans;
Imaging, Three-Dimensional;
Neck;
Organs at Risk;
Particle Accelerators;
Radiotherapy, Intensity-Modulated
- From:Korean Journal of Medical Physics
2008;19(2):89-94
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
TomoTherapy has a merit to treat cancer with Intensity modulated radiation and combines precise 3-D imaging from computerized tomography (CT scanning) with highly targeted radiation beams and rotating beamlets. In this paper, we comparing the dose distribution between TomoTherapy and linear accelerator based intensity modulated radiotherapy (IMRT) for 10 Head & Neck patients using TomoTherapy which is newly installed and operated at National Cancer Center since Sept. 2006. Furthermore, we estimate how the homogeneity and Normal Tissue Complication Probability (NTCP) are changed by motion of target. Inverse planning was carried out using CadPlan planning system (CadPlan R.6.4.7, Varian Medical System Inc. 3100 Hansen Way, Palo Alto, CA 94304-1129, USA). For each patient, an inverse IMRT plan was also made using TomoTherapy Hi-Art System (Hi-Art2_2_4 2.2.4.15, TomoTherapy Incorporated, 1240 Deming Way, Madson, WI 53717-1954, USA) and using the same targets and optimization goals. All TomoTherapy plans compared favorably with the IMRT plans regarding sparing of the organs at risk and keeping an equivalent target dose homogeneity. Our results suggest that TomoTherapy is able to reduce the normal tissue complication probability (NTCP) further, keeping a similar target dose homogeneity.
