Resolution of Chronic Idiopathic Thrombocytopenic Purpura after Eradication of Helicobacter pylori: A Case Report.
- Author:
Dong Seog CHOI
1
;
Yeong Tae SEO
;
Seong Ho CHOI
;
Hye Jin KIM
;
Bong Seog KIM
Author Information
1. Department of Internal Medicine, Seoul Veterans Hospital, Seoul, Korea. seog@e-bohun.or.kr
- Publication Type:Case Report
- Keywords:
Idiopathic thrombocytopenic purpura (ITP);
Helicobacter pylori
- MeSH:
Adenocarcinoma;
Arthritis;
Autoimmune Diseases;
Blood Platelets;
Cytokines;
Epithelial Cells;
Gastritis;
Helicobacter pylori*;
Helicobacter*;
Humans;
Lymphoma, B-Cell, Marginal Zone;
Middle Aged;
Peptic Ulcer;
Prevalence;
Purpura, Schoenlein-Henoch;
Purpura, Thrombocytopenic, Idiopathic*;
Thyroid Diseases
- From:Korean Journal of Hematology
2003;38(4):270-273
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Helicobacter pylori (H. pylori) has been recognized as a main cause of gastritis and most cases of peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. An immunological response to H. pylori infection has been suggested to play a major role in determining gastroduodenal damage through the production of cytokines and the autoantibody against gastric epithelial cell. H. pylori has been implicated in the pathogenesis of some autoimmune disease, such as Sjogren disease, Henoch-Schnlein purpura, rheumatoid arthritis, autoimmune thyroid disease, and idiopathic thrombocytopenic purpura (ITP). Serveral studies recently showed a high prevalence of H. pylori infection in patients with ITP and reported a platelet recovery after bacterial eradication therapy. We report a case of a 54-year-old man with chronic ITP who was resolved after eradication of H. pylori.
