A Case of Solitary Involved NK-T Cell Lymphoma on the Gallbladder.
10.5045/kjh.2009.44.4.268
- Author:
Hee Ja KO
1
;
Mi Yean YANG
;
Han Jo KIM
;
Jin A YUN
;
Hyun Jung KIM
;
Sang Cheol LEE
;
Sang Byung BAE
;
Chan Kyu KIM
;
Nam Su LEE
;
Seong Kyu PARK
;
Kyu Teak LEE
;
Jong Ho WON
;
Dae Sik HONG
;
Hee Sook PARK
;
Hee Kyung KIM
Author Information
1. Department of Internal Medicine, University of Soonchunhyang Collage of Medicine, Bucheon, Korea. skpark@schbc.ac.kr
- Publication Type:Case Report
- Keywords:
Extranodal NK-T cell lymphoma;
Gallbladder cancer;
Non-Hodgkin's lymphoma
- MeSH:
Anal Canal;
Cholecystectomy;
Doxorubicin;
Gallbladder;
Gallbladder Neoplasms;
Humans;
Korea;
Lymphoma;
Lymphoma, Non-Hodgkin;
Middle Aged;
Vincristine
- From:Korean Journal of Hematology
2009;44(4):268-272
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Extranodal NK-T cell lymphoma is a subtype of non-Hodgkin's lymphoma (NHL) and this most commonly affects the nasal and paranasal cavities. Primary lymphoma of the gallbladder is extremely rare and solitary relapsed extranodal NK-T cell lymphoma of the gallbladder has not yet been reported in Korea. We experienced a case of a solitary relapsed extranodal NK-T cell lymphoma of the gallbladder. One year earlier, a 55-year-old man was diagnosed with extranodal NK-T cell lymphoma of the anus, and he underwent six cycles of chemotherapy with CHOP (cyclophosphamide, adriamycin, vincristine and prednisone), and he achieved complete remission. The patient was admitted for right upper quadrant pain. Computed tomography (CT) performed on readmission revealed gallbladder wall thickening. Fluorodeoxyglucose-positron emission tomography (FDG-PET) showed hypermetabolic lesions along the gallbladder wall. The specimen obtained at cholecystectomy revealed CD3(+) and CD56(+) lymphoma, which is characteristic of NK-T cell lymphoma.