Prolonged Extreme Thrombocytosis in a Postsplenectomy Patient with Hereditary Spherocytosis.
10.5045/kjh.2009.44.4.298
- Author:
Yae Min PARK
1
;
Jinny PARK
;
Yunjeong JO
;
Sei Hyun KIM
;
Kwen Chul SHIN
;
In Sik WON
;
Sun Jin SYM
;
Eun Kyung CHO
;
Dong Bok SHIN
;
Jae Hoon LEE
Author Information
1. Department of Internal Medicine, Gachon University of Medicine and Science, Gil Hospital, Incheon, Korea. jhagnes@gilhospital.com
- Publication Type:Case Report
- Keywords:
Reactive thrombocytosis;
Postsplenectomy;
Hereditary spherocytosis
- MeSH:
Adult;
Anemia, Hemolytic;
Cholecystectomy, Laparoscopic;
Female;
Gallstones;
Humans;
Korea;
Osmotic Fragility;
Spherocytosis, Hereditary;
Splenectomy;
Thrombocytosis
- From:Korean Journal of Hematology
2009;44(4):298-303
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a case of prolonged extreme reactive thrombocytosis in a post-splenectomy patient with hereditary spherocytosis. A 29-year-old female patient presented with gall stones detected incidentally by abdominal ultrasonography. Her laboratory findings showed hemolytic anemia with spherocytosis on the peripheral blood smear and increased osmotic fragility. She was diagnosed with hereditary spherocytosis and underwent a laparoscopic cholecystectomy and splenectomy. After undergoing surgery, the hemolytic anemia was resolved but thrombocytosis was newly detected. Nineteen months after the splenectomy, the thrombocytosis was still persistent and extremely high. To our knowledge, this is the first report of a prolonged extreme reactive thrombocytosis after a splenectomy in Korea.
