A Case of Acute Biphenotype Leukemia after Diagnosis of Pulmonary Alveolar Proteinosis.
10.5045/kjh.2009.44.2.117
- Author:
Hong Ryeol CHEONG
1
;
Ha Rin LEE
;
Su Bum PARK
;
Hyo Jeong KIM
;
Na Ri A LEE
;
Jae Hoon CHEONG
;
Mi Ra KIM
;
Young Jin CHOI
;
Joo Seop CHUNG
;
Goon Jae CHO
Author Information
1. Department of Internal Medicine, College of Medicine, Pusan National University, Busan, Korea. chyj@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Pulmonary alveolar proteinosis;
Acute biphenotype leukemia;
B-lymphoid;
Myeloid
- MeSH:
Adult;
Biopsy;
Bone Marrow;
Coloring Agents;
Hematologic Neoplasms;
Humans;
Leukemia;
Lung;
Periodic Acid-Schiff Reaction;
Pulmonary Alveolar Proteinosis;
Thoracoscopes
- From:Korean Journal of Hematology
2009;44(2):117-121
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We present the case of a 34-year-old man with acute biphenotype leukemia that co-expressed B-lymphoid and myeloid antigen after the diagnosis of pulmonary alveolar proteinosis (PAP). The diagnosis of PAP was established by Periodic Acid-Schiff reaction staining on the Video Associated Thoracoscope guided lung biopsy and biphenotype leukemia was revealed by immunohistochemical stains of the blasts harvested from the bone marrow biopsy. Supposedly, PAP follows a hematologic malignancy, yet this case shows the reverse sequence.
