A Case of Multicentric Castleman's Disease Diagnosed with Lymph Node Biopsy and Bone Marrow Examination.
10.5045/kjh.2009.44.3.172
- Author:
Sang Hyuk PARK
1
;
Chan Jeoung PARK
;
Jooryung HUH
;
Seongsoo JANG
;
Hyun Sook CHI
;
Cheolwon SUH
Author Information
1. Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea. cjpark@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Multicentric Castleman's disease;
Lymph node biopsy;
Bone marrow examination
- MeSH:
Ascites;
Biopsy;
Bone Marrow;
Bone Marrow Examination;
Edema;
Fever;
Fever of Unknown Origin;
Giant Lymph Node Hyperplasia;
Lymph Nodes;
Lymphatic Diseases;
Lymphoproliferative Disorders;
Sweat
- From:Korean Journal of Hematology
2009;44(3):172-176
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Castleman's disease (CD) is an uncommon lymphoproliferative disorder presenting with a variable spectrum of clinical manifestations. CD is classified into two subtypes, Localized CD and Multicentric CD, by clinical manifestation, and is divided into 2 histopathologic types: a hyaline-vascular type (HV) or a plasma-cell type (PC). Multicentric CD show PC type predominantly and show systemic symptoms, such as fever, night sweat, malaise, ascites, edema, and more than half show multiple lymphadenopathy and hepatosplenomegaly. We report a case of 67 year old man with multicentric CD presented with fever of unknown origin and diagnosed with lymph node biopsy and bone marrow examination with a brief review of the literature.
