Association of Hemoglobin A1c with Visceral Fat Measured by Computed Tomography in Nondiabetic Adults.
- Author:
A Lum HAN
1
;
Sae Ron SHIN
;
Seong Hoon PARK
;
Jeong Mi LEE
Author Information
1. Department of Family Medicine, Hospital of Wonkwang University, Korea. devilron@naver.com
- Publication Type:Original Article
- Keywords:
Hemoglobin A1c;
Visceral fat;
Prediabetes
- MeSH:
Adult;
Blood Pressure;
Cardiovascular Diseases;
Diabetes Mellitus;
Female;
Health Education;
Hemoglobins;
Humans;
Intra-Abdominal Fat;
Male;
Prediabetic State;
Risk Factors
- From:Journal of Agricultural Medicine & Community Health
2012;37(4):215-222
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: A prediabetes hemoglobin A1c (HbA1c) level of 5.7%-6.4% is considered a risk factor for diabetes mellitus and cardiovascular disease (CVD) in the USA. In this study, we assessed the HbA1c and visceral fat levels as CVD risk factors in health check-up examinees who were not yet diagnosed with diabetes. METHODS: Totally, 507 study subject were categorized as per criteria of the American Diabetes Association, depending on whether the HbA1c level was > or =5.7% or <5.7%. Lipid levels, blood pressure, BMI (kg/m2), total abdominal, and visceral fat levels were measured by computed tomography. RESULTS: The mean of HbA1c in the male group was larger than the mean in the female group and their values were, respectively, 6.03+/-0.8% and 5.88+/-0.72%(p<0.05). Only the mean values of age and visceral fat area were different between HbA1c> or =5.7% and <5.7% in both male and female group (p<0.05). Visceral fat levels were significantly associated with HbA1c in the group of HbA1c > or =5.7% (odds ratio=1.005, 95% CI 1.002~1.008). CONCLUSIONS: Visceral fat levels were significantly higher and correlated with the group which HbA1c level is > or =5.7%. This finding suggests that subjects who have high levels of HbA1c should be carefully monitored during prediabetes and should have chance to have health education programs.