Vein valve function following pharmacomechanical thrombectomy versus simple catheter-directed thrombolysis for lower extremity deep vein thrombosis: A case control study
10.7507/1007-4848.201805005
- VernacularTitle:药物机械碎栓和导管接触性溶栓对下肢深静脉血栓患者股静脉瓣膜功能影响的病例对照研究
- Author:
CHENG Zhangbo
1
;
DING Hang
1
;
REN Fei
1
;
LAN Yongrong
1
;
LI Chunping
1
;
LEI Yunhong
1
;
HAN Tao
1
Author Information
1. Department of Cardiovascular Surgery, Fujian Provincial Hospital, Fuzhou, 350001, P.R.China
- Publication Type:Journal Article
- Keywords:
Deep vein thrombosis;
pharmacomechanical thrombolysis;
catheter-directed thrombolysis;
femoral vein valve function
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2019;26(2):148-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare vein valve function following pharmacomechanical thrombolysis (PMT) with simple catheter-directed thrombolysis (CDT) for deep vein thrombosis. Methods We retrospectively analyzed the clinical data of sixty patients who suffered acute lower extremity deep vein thrombsis in our hospital between October 2016 and March 2017. All patients underwent contralateral preprocedural duplex and bilateral postprocedure duplex to access patency and valve function. The patients were divided into three groups including a group A with catheter-directed thrombolysis (CDT) alone (36 patients with 20 males and 16 females at average age of 56 years), a group B with PMT alone (15 patients with 8 males and 7 females at average age of 55 years), and a group C with PMT combined CDT (9 patients with 4 males and 5 females at average age of 56 years). The valve function was compared among the Group A, Group B and Group C. Results There were 40.0% (24/60) patients with bilateral femoral vein valve reflux, 40.0% (24/60) patients with unilateral femoral vein valve reflux (all in the treated limbs), 20% (12/60) patients had no reflux in both limbs. Of the limbs treated with CDT alone, PMT alone and PMT combined CDT, the rate of valve reflux was 38.9% (14/36), 33.3% (5/15), and 55.6% (5/9) respectively (P=0.077). Conclusion In the patients suffering acute DVT, PMT or PMT combined CDT does not hamper valve function compared with CDT alone.
