Protective effect of thymosin β4 in ocular surface diseases
10.3980/j.issn.1672-5123.2019.3.12
- VernacularTitle:胸腺肽β4在眼表疾病中的保护作用
- Author:
Jing-Hua Liu
1
Author Information
1. 1Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300070, China; 2Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China
- Publication Type:Journal Article
- Keywords:
thymosin β4;
ocular surface diseases;
protective functions
- From:
International Eye Science
2019;19(3):402-404
- CountryChina
- Language:Chinese
-
Abstract:
Thymosin is a kind of protein that is widely distributed in many tissues. It has many biological activities. Thymosin is divided into three subtypes: thymosin α, thymosin β and thymosin γ. Thymosin β4(Tβ4)is the most widely distributed in normal human body. A large number of studies have confirmed that Tβ4 has the functions of anti-inflammatory, anti-apoptosis and promoting proliferation. Ocular surface diseases are mostly related to ocular surface injury and inflammation. Therefore, promoting wound repair and healing and anti-inflammatory are the key to the treatment of ocular surface diseases. The present review mainly introduces the distribution, structure, synthesis of Tβ4 and its protective effect on ocular surface.
