Protective effect of thymosin β4 in ocular surface diseases
10.3980/j.issn.1672-5123.2019.3.12
- VernacularTitle:胸腺肽β4在眼表疾病中的保护作用
- Author:
Jing-Hua Liu
1
,
2
Author Information
1. 1Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300070, China
2. 2Tianjin Eye Hospital, Tianjin Eye Institute, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin 300020, China
- Publication Type:Journal Article
- Keywords:
thymosin β4;
ocular surface diseases;
protective functions
- From:
International Eye Science
2019;19(3):402-404
- CountryChina
- Language:Chinese
-
Abstract:
Thymosin is a kind of protein that is widely distributed in many tissues. It has many biological activities. Thymosin is divided into three subtypes: thymosin α, thymosin β and thymosin γ. Thymosin β4(Tβ4)is the most widely distributed in normal human body. A large number of studies have confirmed that Tβ4 has the functions of anti-inflammatory, anti-apoptosis and promoting proliferation. Ocular surface diseases are mostly related to ocular surface injury and inflammation. Therefore, promoting wound repair and healing and anti-inflammatory are the key to the treatment of ocular surface diseases. The present review mainly introduces the distribution, structure, synthesis of Tβ4 and its protective effect on ocular surface.
