Cesarean section does not increase the prevalence of allergic disease within 3 years of age in the offsprings.
- Author:
Hye In KIM
1
;
SeonMi NAM
;
Yejin PARK
;
Yun Ji JUNG
;
Ha Yan KIM
;
Kyung Won KIM
;
Myung Hyun SOHN
;
Young Han KIM
;
Joon Ho LEE
;
Soo Jong HONG
;
Ja Young KWON
Author Information
- Publication Type:Original Article
- Keywords: Allergic disease; Infant; Cesarean section; Labor
- MeSH: Asthma; Birth Weight; Breast Feeding; Cesarean Section*; Cohort Studies; Confounding Factors (Epidemiology); Diagnosis; Female; Follow-Up Studies; Gestational Age; Humans; Infant; Infant, Newborn; Intensive Care, Neonatal; Medical Records; Membranes; Parity; Parturition; Pregnancy; Prevalence*; Rupture; Seasons
- From:Obstetrics & Gynecology Science 2019;62(1):11-18
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: In this study, we evaluated the prevalence of allergic disease in offsprings delivered via the delivery modes of vaginal delivery vs. planned Cesarean section vs. Cesarean section with labor. METHODS: This study included 175 mother-neonate pairs from Severance Hospital who were enrolled in the Cohort for Childhood Origin of Asthma and allergic diseases study. Information regarding prenatal environmental factors, delivery, and diagnosis of allergic diseases was obtained from a questionnaire and medical record review. Patients with at least 3 years of follow-up data were included in this study. Results were adjusted for sex, birth weight, gestational age at birth, season of birth, neonatal intensive care unit admission, parity, breastfeeding, and maternal factors. RESULTS: A total of 175 offsprings were eligible for analysis. Among the subjects, 52.0% were delivered by vaginal delivery, 34.3% by planned Cesarean section, and 16.6% by Cesarean section with labor. Fifty-nine offsprings (33.7%) were diagnosed with allergic disease at a median age of 1 year (range 0.5–3 years). The prevalence of allergic disease was not associated with delivery mode after adjusting for confounding variables. Time period from membrane rupture to delivery, duration of the active phase, and the beginning of the pelvic division prior to Cesarean section were not associated with allergic disease development in offsprings. CONCLUSION: Cesarean section, irrespective of the occurrence of labor before surgery, did not increase the prevalence of allergic disease in infants up to 3 years of age.
