Effect of High β-glucan Barley on Postprandial Blood Glucose Levels in Subjects with Normal Glucose Tolerance: Assessment by Meal Tolerance Test and Continuous Glucose Monitoring System.
- Author:
Mariko HIGA
1
;
Yukie FUSE
;
Naoko MIYASHITA
;
Asami FUJITANI
;
Kaoru YAMASHITA
;
Takamasa ICHIJO
;
Seiichiro AOE
;
Takahisa HIROSE
Author Information
- Publication Type:Original Article
- Keywords: Diet therapy; Beta glucan; Barley; Postprandial hyperglycemia; Glucose monitoring; Meal tolerance
- MeSH: Blood Glucose*; Diet Therapy; Eating; Glucose*; Healthy Volunteers; Hordeum*; Humans; Hyperglycemia; Male; Meals*
- From:Clinical Nutrition Research 2019;8(1):55-63
- CountryRepublic of Korea
- Language:English
- Abstract: The effect of white rice (WR) mixed with high β-glucan-containing barley at 50% on improvement of postprandial blood glucose levels was assessed by meal tolerance test and continuous glucose monitoring (CGM) in 15 healthy subjects with normal glucose tolerance (age 31.6 ± 12.9 years old, 4 males and 11 females). A meal tolerance test (500 kcal) was conducted using 2 types of test meals: a test meal only with WR and a test meal WR mixed 50% barley, and the side dish was the same in both meals. Blood glucose levels of the subjects 180 minutes after ingestion of the test meals were compared. In addition, a CGM device was attached to the subjects for 2 days when the WR or barley as a staple food was provided 3 times a day for consecutive days, and the daily variation of glucose was investigated. The glucose levels 30 minutes after dietary loads and the area under the blood concentration-time curve over 180 minutes were significantly decreased in the barley consumption group. In CGM, 24-hour mean blood glucose and 24-hour standard deviation of blood glucose were also significantly decreased after ingestion of the barley. Postprandial glucose level elevation was suppressed by mixing high-β-glucan barley with WR in subjects with normal glucose tolerance.
