Analysis of Relationship between Reflux Symptom Index and Psychiatric Problems.
10.3342/kjorl-hns.2017.00738
- Author:
In Jun PARK
1
;
Jun Myung KANG
;
Jae Hyun SEO
;
Se Hwan HWANG
;
Ho Young YOUN
;
Ho Jun JIN
;
Ha Ram KANG
;
Young Hoon JOO
Author Information
1. Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea. joodoct@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Anxiety;
Depression;
Laryngopharyngeal reflux;
Somatoform disorders
- MeSH:
Airway Obstruction;
Anxiety;
Depression;
Heartburn;
Humans;
Laryngopharyngeal Reflux;
Methods;
Multivariate Analysis;
Prospective Studies;
Somatoform Disorders
- From:Korean Journal of Otolaryngology - Head and Neck Surgery
2018;61(12):692-696
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: This study investigated the relationship between reflux symptom index (RSI) and psychiatric problems such as depression, somatization, and anxiety. SUBJECTS AND METHOD: We prospectively analyzed 231 patients with symptoms with laryngopharyngeal reflux (LPR) using the RSI and the reflux finding score. RESULTS: Seventy nine patients (34.2%) were diagnosed with LPR. A significant correlation was detected between the RSI and depression (18.4±8.3 vs. 12.3±7.0, p < 0.001), anxiety (19.5±8.5 vs. 13.0±7.3, p < 0.001), and somatization (19.2±9.1 vs. 13.6±7.5, p < 0.001). A multivariate analysis confirmed a significant association between heartburn and depression [odds ratio (OR): 1.241, 95% confidence interval (CI): 1.003–1.537, p=0.047], choking and anxiety (OR: 1.747, 95% CI: 1.297–2.352, p < 0.001), and choking and somatization (OR: 1.707, 95% CI: 1.248–2.336, p=0.001). CONCLUSION: Our preliminary results suggest that patients with high RSI may need to be carefully evaluated for psychiatric problems.
