A Case of Malignant External Otitis with Pichia ohmeri.
- Author:
Jun Seong SON
1
;
Sang Yop SHIN
;
Tae Hoon MIN
;
Hyun Ha CHANG
;
Sook In JUNG
;
Won Sup OH
;
Sung Min KIM
;
Kyong Ran PECK
;
Jae Hoon SONG
Author Information
1. Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jhsong@smc.samsung.co.kr
- Publication Type:Case Report
- Keywords:
Pichia ohmeri;
Malignant external otitis;
Pathogen
- MeSH:
Biopsy;
Ear;
Earache;
Fluconazole;
Fungemia;
Hearing;
Humans;
Hypertension;
Magnetic Resonance Imaging;
Mastoid;
Osteomyelitis;
Otitis Externa*;
Peritonitis;
Pichia*;
Skull Base
- From:Korean Journal of Infectious Diseases
2002;34(5):349-353
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pichia ohmeri is a rare fungal pathogen for human infection. To date, only 5 cases of P. ohmeri infection have been reported including fungemia, disseminated infection and peritonitis. We report the first case of malignant external otitis and mastoid osteomyelitis caused by P. ohmeri. The patient had a long history of diabetes, hypertension and arrrhythmia. The patient was admitted to the hospital because of otorrhea, otalgia and hearing difficulty for 3 months. Internal auditory canal MRI showed osteomyelitis of left mastoid bone and skull base. Culture of ear discharge and bone biopsy specimen grew P. ohmeri. The patient had been treated with amphotericin-B followed by fluconazole.