Surgical Outcomes of Radiographically Noninvasive Lung Adenocarcinoma according to Surgical Strategy: Wedge Resection, Segmentectomy, and Lobectomy.
10.5090/kjtcs.2018.51.6.376
- Author:
Keong Jun HA
1
;
Jae Kwang YUN
;
Geun Dong LEE
;
Won Chul CHO
;
Se Hoon CHOI
;
Hyeong Ryul KIM
;
Yong Hee KIM
;
Dong Kwan KIM
;
Seung Il PARK
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Gangneung Asan Hospital, University of Ulsan College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Adenocarcinoma;
Nodules, solitary pulmonary;
Lobectomy;
Chest;
Computed tomography
- MeSH:
Adenocarcinoma*;
Disease-Free Survival;
Humans;
Lung*;
Mastectomy, Segmental*;
Retrospective Studies;
Solitary Pulmonary Nodule;
Thorax
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2018;51(6):376-383
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The aim of this study was to evaluate the outcomes of surgical resection in patients with radiographically noninvasive lung adenocarcinoma according to the surgical strategy. METHODS: A retrospective study was conducted of 128 patients who underwent pulmonary resection for ground-glass opacity (GGO)–dominant nodules measuring ≤2 cm with a consolidation/tumor ratio ≤0.25 based on computed tomography between 2008 and 2015. The 5-year disease-free survival (DFS) rate and 5-year overall survival (OS) rate were analyzed. RESULTS: Among the 128 patients, wedge resection, segmentectomy, and lobectomy were performed in 40 (31.2%), 22 (17.2%), and 66 patients (51.6%), respectively. No significant differences were found among the groups in the mean size of tumors (p=0.119), the rate of pure-GGO nodules (p=0.814), the consolidation/tumor ratio (p=0.695), or the rate of invasive adenocarcinoma (p=0.378). Centrally located tumors were more common in the lobectomy group (21.2%) than in the wedge resection (0%) or segmentectomy (0%) groups (p=0.001). There were no significant differences in the 5-year DFS rate (100%, 100%, 92.7%, respectively; p=0.76) or 5-year OS rate (100%, 100%, 100%; p=0.223) among the wedge resection, segmentectomy, and lobectomy groups. CONCLUSION: For radiographically noninvasive lung adenocarcinoma measuring ≤2 cm with a consolidation/tumor ratio ≤0.25, wedge resection and segmentectomy could be comparable surgical options to lobectomy.
