Granulocytic sarcoma presenting in two patients without leukemia.
- Author:
Kyu Ho LEE
1
;
Hyun KIM
;
Guan Yong CHOI
;
Ju Hee LEE
;
Hye Suk HAN
;
Ki Hyeong LEE
;
Seung Taik KIM
Author Information
1. Department of Internal Medicine, Chungbuk National University College of Medicine, Cheongju, Korea. kihlee@chungbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Granulocytic sarcoma;
Abdominal mass;
Spinal cord compression
- MeSH:
Abdomen;
Adrenal Glands;
Adult;
Bone Marrow;
Diagnosis, Differential;
Humans;
Leukemia;
Magnetic Resonance Imaging;
Sarcoma, Myeloid;
Spinal Canal;
Spinal Cord Compression;
Spinal Cord Neoplasms
- From:Korean Journal of Medicine
2009;77(2):236-240
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Granulocytic sarcoma (GS) is a rare extramedullary tumor composed of immature myeloid precursor cells. GS is associated with acute or chronic myeloid leukemia; it has rarely been reported in non-leukemic patients. We report two cases of GS with unusual presentations; neither had bone marrow involvement. The first case was a GS presenting with multiple intra-abdominal masses in a 43-year-old man. Computed tomography (CT) of the abdomen showed masses in the small bowel and right adrenal gland. The second case was a patient with a GS presenting with symptoms of spinal cord compression in a 32-year-old man. Magnetic resonance imaging (MRI) showed an extradural mass in the spinal canal at the T3-T5 levels. Blood smear and bone marrow studies were normal. These cases show that GS should be included in the differential diagnosis of intra-abdominal masses and extradural spinal cord tumors, even in the absence of leukemia.
