- Author:
You Ho MUN
1
;
Jung Ho KIM
Author Information
- Publication Type:Case Report
- Keywords: Methamphetamine; Cardiac arrest; Resuscitation; Rhabdomyolysis
- MeSH: Acute Kidney Injury; Adult; Cardiopulmonary Resuscitation; Chest Pain; Dyspnea; Emergencies; Emergency Service, Hospital; Heart Arrest*; Humans; Korea; Male; Methamphetamine*; Outpatients; Plasma; Poisoning*; Renal Insufficiency, Chronic; Renal Replacement Therapy; Resuscitation; Rhabdomyolysis; Seizures; Substance-Related Disorders
- From:Journal of The Korean Society of Clinical Toxicology 2018;16(2):176-180
- CountryRepublic of Korea
- Language:Korean
- Abstract: Drug abuse and its related problems are increasing continuously in Korea. One of the most frequently abused drugs is methamphetamine, but there are few medical report in Korea. This is the first report of the identification of methamphetamine in the blood of a patient who had a return of spontaneous circulation after cardiac arrest and survived discharge. A 33-year-old male arrived at the emergency department presenting with chest pain and dyspnea. He had ingested methamphetamine and alcohol approximately 7 hours before arrival. One hour after arrival, he had seizure followed by cardiac arrest. Spontaneous circulation was recovered after 4 minutes of CPR. An analysis of the National Forensic Service identified plasma methamphetamine with an estimated average concentration of plasma methamphetamine at the time of arrival of 0.6 mg/L, a lethal dose. He had rhabdomyolysis and acute kidney injury but survived after continuous renal replacement therapy. Since then, he has suffered chronic kidney disease, and he is being followed up at the out-patient department. In Korea, although drug abuse is still uncommon, it is on the increase. Therefore, emergency physicians should be aware of the clinical characteristics of methamphetamine poisoning.