Change in Quality of Life according to the Change in Atopic Dermatitis Severity.
10.7581/pard.2012.22.1.86
- Author:
Joongbum CHO
1
;
Jung Hyun LEE
;
Jungmin SUH
;
Jung Seok YU
;
Hoseok LEE
;
Eunah PARK
;
Hyunmi KIM
;
Eun Young CHANG
;
Jihyun KIM
;
Youngshin HAN
;
Kangmo AHN
Author Information
1. Department of Pediatrics, Korea Cancer Center Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Asthma;
Allergic rhinitis;
Atopic dermatitis;
Immunoglobulin E;
Allergen-specific IgE
- MeSH:
Asthma;
Dermatitis;
Dermatitis, Atopic;
Dermatology;
Food Hypersensitivity;
Humans;
Immunoglobulin E;
Longitudinal Studies;
Prospective Studies;
Quality of Life;
Surveys and Questionnaires;
Rhinitis, Allergic, Perennial
- From:Pediatric Allergy and Respiratory Disease
2012;22(1):86-99
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to longitudinally examine the correlation between the change of atopic dermatitis (AD) severity and the change of quality of life (QOL). METHODS: We assessed AD severity and QOL of patients and their families, by a prospective followed up for at least 12 months. AD severity was assessed, using the scoring of atopic dermatitis (SCORAD) index. A questionnaire based on dermatitis family impact (DFI), infants' dermatologic quality of life (IDQoL) and children's dermatology life quality index (CDLQI) were used to determine QOL. RESULTS: Seventy-nine AD patients were assessed for total and objective SCORAD and DFI. Among them, 45 patients that were less than 36 months old completed IDQoL and 13 patients that were equal to or more than 36 months old completed CDLQI. Objective SCORAD (oSCORAD) were correlated with DFI (r=0.235), IDQoL (r=0.602) and CDLQI (r=0.589) (P<0.05). At the 2nd interview, median oSCORAD (from 17.4 to 7.8), DFI (from 23.0 to 18.0) and IDQoL (from 9.0 to 6.0) were significantly decreased (P<0.01). The changes of oSCORAD were linearly related with the change of IDQoL (P<0.01), but neither with DFI (P=0.356) nor with CDLQI (P=0.267). Of the 64 patients with decreased oSCORAD, food allergy was accompanied more frequently in those with an increased DFI than those with a decreased DFI (60.7% vs. 27.8%, P<0.01). CONCLUSION: In this longitudinal study, the improvement of AD severity is correlated with the improvement of the patient's QOL, under the age of 3. To improve the family's QOL, we need to find out accompanying factors, such as food allergy, and to support the family accordingly.
