Long-term Outcomes of Augmentation Cystoplasty in a Pediatric Population With Refractory Bladder Dysfunction: A 12-Year Follow-up Experience at Single Center.
- Author:
Shahbaz MEHMOOD
1
;
Hamdan ALHAZMI
;
Mohammed AL-SHAYIE
;
Ahmed ALTHOBITY
;
Ahmed ALSHAMMARI
;
Waleed Mohamed ALTAWEEL
;
Ahmed ALMATHAMI
;
Santiago VALLASCIANI
Author Information
- Publication Type:Original Article
- Keywords: Augmentation cystoplasty; Bladder dysfunction; Physical growth; Urinary bladder calculi
- MeSH: Adult; Child; Compliance; Follow-Up Studies*; Humans; Ileum; Lost to Follow-Up; Male; Retrospective Studies; Urinary Bladder Calculi; Urinary Bladder*; Weight Gain
- From:International Neurourology Journal 2018;22(4):287-294
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: Augmentation cystoplasty (AC) is a surgical procedure used in adults and children with refractory bladder dysfunction, including a small bladder capacity and inadequate bladder compliance, and in whom conservative and medical treatment has failed. This study was aimed to determine the long-term outcomes of AC in children. METHODS: A retrospective analysis was conducted of 42 patients (31 males; mean age, 14.2±6.2 years) who underwent AC for neurogenic and nonneurogenic bladder dysfunction, with a median 12.0±1.5 years of follow-up. All patients underwent AC using the ileum with or without continent reconstruction. Pre-AC, concurrent, and post-AC procedures and complications were analyzed. Patients who underwent ureterocystoplasty, were lost to follow-up, or had less than 10 years of follow-up were excluded. The primary outcomes were the complication and continence rates, the post-AC linear rate of height and weight gain, and renal function. The Student t-test was used to evaluate between-group differences and the paired t-test was used to evaluate longitudinal changes in measured variables. RESULTS: Renal function was stable or improved in 32 of 42 patients (76.2%), with a post-AC continence rate of 88.1%. Thirty patients (71.4%) required 72 procedures post-AC. There was no statistically significant difference in the mean percentile of height (P=0. 212) or weight (P=0.142) of patients in the pre- and post-AC periods. No cases of bladder perforation or malignancy were detected. CONCLUSIONS: We consider AC to be a safe and effective procedure that does not negatively affect future physical growth, while achieving a good rate of stable renal function. Patients need long-term follow-up to address long-term complications.
