Bone marrow-derived stem cells contribute to regeneration of the endometrium.
10.5653/cerm.2018.45.4.149
- Author:
Youn Jeong LEE
1
;
Kyong Wook YI
Author Information
1. Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea. kwyi@korea.ac.kr
- Publication Type:Review
- Keywords:
Bone marrow;
Endometrium;
Stem cells
- MeSH:
Bone Marrow;
Cell Lineage;
Endometrium*;
Female;
Humans;
Physiology;
Regeneration*;
Stem Cells*;
Therapeutic Uses;
Uterus
- From:Clinical and Experimental Reproductive Medicine
2018;45(4):149-153
- CountryRepublic of Korea
- Language:English
-
Abstract:
Stem cells are undifferentiated cells capable of self-renewal and differentiation into various cell lineages. Stem cells are responsible for the development of organs and regeneration of damaged tissues. The highly regenerative nature of the human endometrium during reproductive age suggests that stem cells play a critical role in endometrial physiology. Bone marrow-derived cells migrate to the uterus and participate in the healing and restoration of functionally or structurally damaged endometrium. This review summarizes recent research into the potential therapeutic effects of bone marrow-derived stem cells in conditions involving endometrial impairment.
