Outcomes of transcatheter closure of ductus arteriosus in infants less than 6 months of age: a single-center experience.
- Author:
Gwang Jun CHOI
1
;
Jinyoung SONG
;
Yi Seul KIM
;
Heirim LEE
;
June HUH
;
I Seok KANG
Author Information
- Publication Type:Original Article
- Keywords: Congenital heart disease; Patent ductus arteriosus; Transcatheter closure
- MeSH: Angiography; Aortic Coarctation; Classification; Ductus Arteriosus*; Ductus Arteriosus, Patent; Heart Defects, Congenital; Humans; Incidence; Infant*; Intubation; Retrospective Studies; Vascular System Injuries
- From:Korean Journal of Pediatrics 2018;61(12):397-402
- CountryRepublic of Korea
- Language:English
- Abstract: PURPOSE: Transcatheter device closure of patent ductus arteriosus (PDA) is challenging in early infancy. We evaluated PDA closure in infants less than 6 months old. METHODS: We performed a retrospective review of infants less than 6 months of age who underwent attempted transcatheter device closure in our institution since 2004. To compare clinical outcomes between age groups, infants aged 6–12 months in the same study period were reviewed. RESULTS: A total of 22 patients underwent transcatheter PDA closure during the study period. Patient mean age was 3.3±1.5 months, and weight was 5.7±1.3 kg. The duct diameter at the narrowest point was 3.0±0.8 mm as measured by angiography. The most common duct type was C in the Krichenko classification. Procedural success was achieved in 19 patients (86.3%). Major complications occurred in 5 patients (22.7%), including device embolization (n=1), acquired aortic coarctation (n=2), access-related vascular injury requiring surgery (n=1), and acute deterioration requiring intubation during the procedure (n=1). Two patients had minor complications (9.1%). Twenty-four infants aged 6–12 months received transcatheter device closure. The procedural success rate was 100%, and there were no major complications. The major complication rate was significantly higher in the group less than 6 months of age (P=0.045). There was a trend toward increased major complication and procedural failure rates in the younger age group (P < 0.01). CONCLUSION: A relatively higher incidence of major complications was observed in infants less than 6 months of age. The decision regarding treatment modality should be individualized.
