Lesion Characteristics of Mitral Valve Prolapse due to Myxomatous Degeneration in Korea: A Prospective Multicenter Study Using Echocardiography.
10.4070/kcj.2005.35.12.904
- Author:
Jae Kwan SONG
1
;
Jong Min SONG
;
Yun Jeong KIM
;
Soo Jin KANG
;
Duk Hyun KANG
;
Shung Chull CHAE
;
Heung Sun KANG
;
Jong Hoa BAE
;
Kee Sik KIM
;
Wan Joo SHIM
;
Jin Won JEONG
;
Jong Chun PARK
;
Kyoung Sig CHANG
;
Jae Whan LEE
;
In Whan SEONG
;
Eun Ju CHO
;
Ho Joong YOUN
;
Sang Chol LEE
;
Seung Woo PARK
;
Jong Won HA
;
Se Joong LIM
;
Namsik CHUNG
;
Yong Jin KIM
;
Dae Won SOHN
Author Information
1. Division of Cardiology, Asan Medical Center, Seoul, Korea. jksong@amc.seoul.kr
- Publication Type:Multicenter Study ; Original Article
- Keywords:
Mitral valve prolapse;
Echocardiography
- MeSH:
Echocardiography*;
Echocardiography, Transesophageal;
Humans;
Hypertension;
Korea*;
Male;
Mitral Valve Insufficiency;
Mitral Valve Prolapse*;
Mitral Valve*;
Pectinidae;
Prevalence;
Prolapse;
Prospective Studies*;
Rupture
- From:Korean Circulation Journal
2005;35(12):904-909
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND AND OBJECTIVES: We sought to characterize the lesion characteristics of mitral valve prolapse (MVP), which is being increasingly recognized as a cause of mitral regurgitation (MR) in Koreans SUBJECTS AND METHODS: 497 Patients with MVP that was diagnosed by echocardiography in 13 university-affiliated hospitals from Jan to Dec 2003 were prospectively enrolled in our study. RESULTS: A total of 497 patients (270 males, 54%) were enrolled and their mean age was 52+/-17 years. Grade 4 MR was present in 272 patients (54.7%); grade 3, 2 and 1 MR as present in 30.2%, 10.7% and 4.2%, respectively. MVP of the anterior and posterior mitral leaflet was present in 170 patients (34.2%) and 223 patients (44.9%), respectively; MVP developed in both leaflets in 104 patients (20.9%). In 37 patients (7.4%), MVP developed in all 6 segments of the mitral leaflet and these patients were younger (37+/-14 versus 54+/-16 years, respectively, p<0.05) and had a lower prevalence of chordae rupture and severe MR compared to the other patients. Among the 266 mitral segments showing prolapse in the 132 patients (26.6%) who underwent transesophageal echocardiography, the posterior medial scallop was the most frequently diseased one (26%), and this was followed by the posterior middle scallop (18%), the medial (17%), lateral (14%) and middle (13%) part of the anterior leaflet, and the posterior lateral scallop (12%). Younger patients with a mean age <45 years showed a lower prevalence of single segment prolapse, hypertension, severe MR and chordae rupture compared to the older patients (p<0.001, each). CONCLUSION: The medial part of both mitral leaflets was the predilection site for the development of MVP in Koreans and the lesion characteristics were different according to the patients' age.
