Comprehensive Laboratory Analysis of Korean Acute Alcoholic Intoxication Patients Reveals the Need for a National Hepatitis B Virus Vaccination Program in Korea.
- Author:
Sang Yong SHIN
1
Author Information
- Publication Type:Original Article
- Keywords: Alcoholic Intoxication; Chronic Disease; Hepatitis B Virus; Korea
- MeSH: Alcoholic Intoxication*; Alcoholics*; Anemia; Anemia, Macrocytic; Chronic Disease; Emergency Service, Hospital; Glomerular Filtration Rate; Hepatitis B Surface Antigens; Hepatitis B virus*; Hepatitis B*; Hepatitis*; Humans; Korea*; Male; Public Health; Renal Insufficiency, Chronic; Retrospective Studies; Serum Albumin; Thrombocytopenia; Vaccination
- From:Korean Journal of Family Medicine 2018;39(6):360-363
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Acute alcoholic intoxication patients (AAIP) are a common public health problem. The aim of this study was to perform a comprehensive laboratory analysis for these patients to investigate the co-morbid medical problem. METHODS: We retrospectively reviewed laboratory findings of AAIP who were transferred to the emergency department (ED) from January 2017 to June 2017. RESULTS: A total of 160 male patients were enrolled. Sixteen patients (16/160, 10.0%) and three patients (3/160, 1.9%) had macrocytic anemia and microcytic anemia, respectively. A total of 33 patients (33/160, 20.6%) showed thrombocytopenia ( < 150×109/L). Twelve patients (12/159, 7.5%) showed low serum albumin level ( < 3.5 g/dL). Three patients (3/160, 1.9%) had chronic kidney disease stages 3–4 based on estimated glomerular filtration rate. Six patients (6/27, 22.2%) had high hemoglobin A1c (HbA1c) level (>7.0%). Positive rates of hepatitis B surface antigen and anti-HBs antibody (anti-HBs Ab) were 3.5% (5/141) and 49.0% (68/141), respectively. CONCLUSION: Patients with AAIP who were transferred to ED had various laboratory abnormalities (anemia, thrombocytopenia, high HbA1c). They had low positive rate of anti-HBs Ab. This might be a public health problem, suggesting the need of hepatitis B virus vaccination program for AAIP. Our data suggest the need of further nationwide studies.
