A Case of Refractory Vitiligo Treated with Non-cultured Epidermal Cell Suspension Transplantation Using Suction Blister Method.
- Author:
Sung Hye EUN
1
;
Yu Seok JUNG
;
Hanna LEE
;
Ji Hae LEE
;
Gyong Moon KIM
;
Jung Min BAE
Author Information
1. Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea. jminbae@gmail.com
- Publication Type:Case Report
- Keywords:
Non-cultured epidermal cell suspension transplantation;
Suction blister;
Vitiligo
- MeSH:
Adolescent;
Blister*;
Cicatrix;
Coinfection;
Female;
Hematopoietic Stem Cell Transplantation;
Humans;
Leg;
Methods*;
Phototherapy;
Precursor Cell Lymphoblastic Leukemia-Lymphoma;
Suction*;
Thigh;
Tissue Donors;
Vitiligo*
- From:Korean Journal of Dermatology
2018;56(9):552-555
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Vitiligo is a commonly acquired cutaneous depigmentation disorder that affects 0.5~1% of the population worldwide. While phototherapy is the primary treatment for vitiligo, surgical methods can be used for treating patients who are refractory to conventional treatments. Herein, we present the case of a 14-year-old Korean girl who developed vitiligo after hematopoietic stem cell transplantation for the treatment of acute lymphoblastic leukemia. She had multiple depigmented patches on her lower legs that did not respond to narrow-band ultraviolet B phototherapy for 7 months. The depigmented patches were successfully treated by transplantation of non-cultured epidermal cell suspension from the epidermal roof of the suction blister in the right inner thigh. No adverse event, such as secondary infection or scarring in both the donor and recipient sites, was noted. We recommended that non-cultured epidermal cell suspension transplantation using the suction blister method would be a safe and effective option for the treatment of refractory vitiligo.
