Which Index for Muscle Mass Represents an Aging Process?.
10.11005/jbm.2018.25.4.219
- Author:
Hyung Kook KIM
1
;
You Jin LEE
;
Young Kyun LEE
;
Hongji KIM
;
Kyung Hoi KOO
Author Information
1. Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. ykleemd@gmail.com
- Publication Type:Original Article
- Keywords:
Aging;
Sarcopenia
- MeSH:
Aging*;
Biomarkers;
Body Mass Index;
Bone Density;
Cross-Sectional Studies;
Female;
Hearing;
Humans;
Korea;
Male;
Muscle, Skeletal;
Nutrition Surveys;
Retrospective Studies;
Sarcopenia;
Visual Acuity
- From:Journal of Bone Metabolism
2018;25(4):219-226
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Although studies and interest in sarcopenia have increased, it is still a matter of debate which muscle mass index better represents the aging process. We compared 3 indices for muscle mass (appendicular skeletal muscle mass [ASM]/weight, ASM/height2, and the body mass index [BMI]-adjusted muscle mass index [ASM/BMI]) to determine which better reflected the aging process in terms of the decline in bone mineral density (BMD), visual acuity (VA), hearing power, renal function, pulmonary function, and handgrip strength. METHODS: We performed a retrospective cross-sectional study using the Korea National Health and Nutrition Examination Survey in the Korean population. Between 2008 and 2011, a total of 14,415 men and 17,971 women aged 10 years or older participated in the study. We plotted the changes in the 3 indices of muscle mass and compared these with changes in BMD, VA, hearing power, renal function, pulmonary function, and handgrip strength according to each age group. RESULTS: The ASM/BMI showed similar changes in terms of surrogate markers of the aging process, while the ASM/weight and ASM/height2 showed no correlation. CONCLUSIONS: Among muscle indices for sarcopenia, only the ASM/BMI represented the aging process.
