Pollen-Food Allergy Syndrome in Korean Pollinosis Patients: A Nationwide Survey.
10.4168/aair.2018.10.6.648
- Author:
Mi Ae KIM
1
;
Dong Kyu KIM
;
Hyeon Jong YANG
;
Young YOO
;
Youngmin AHN
;
Hae Sim PARK
;
Hyun Jong LEE
;
Yi Yeong JEONG
;
Bong Seong KIM
;
Woo Yong BAE
;
An Soo JANG
;
Yang PARK
;
Young Il KOH
;
Jaechun LEE
;
Dae Hyun LIM
;
Jeong Hee KIM
;
Sang Min LEE
;
Yong Min KIM
;
Young Joon JUN
;
Hyo Yeol KIM
;
Yunsun KIM
;
Jeong Hee CHOI
Author Information
1. Department of Pulmonology, Allergy and Critical Care Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Korea.
- Publication Type:Original Article
- Keywords:
Pollen-food allergy syndrome;
pollen;
food allergy
- MeSH:
Adult;
Ananas;
Anaphylaxis;
Arachis;
Asthma;
Codonopsis;
Crowns;
Cucurbitaceae;
Food Hypersensitivity;
Fruit;
Humans;
Hypersensitivity*;
Immunoglobulin E;
Immunoglobulins;
Juglans;
Korea;
Lotus;
Lycopersicon esculentum;
Neurologic Manifestations;
Perilla;
Pollen;
Prevalence;
Prunus armeniaca;
Prunus domestica;
Prunus persica;
Pueraria;
Research Personnel;
Rhinitis, Allergic, Seasonal*;
Skin;
Vegetables
- From:Allergy, Asthma & Immunology Research
2018;10(6):648-661
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Pollen-food allergy syndrome (PFAS) is an immunoglobulin E (IgE)-mediated allergy in pollinosis patients caused by raw fruits and vegetables and is the most common food allergy in adults. However, there has been no nationwide study on PFAS in Korea. In this study, we investigated the prevalence and clinical characteristics of PFAS in Korea. METHODS: Twenty-two investigators participated in this study, in which patients with allergic rhinoconjunctivitis and/or bronchial asthma with pollen allergy were enrolled. The questionnaires included demographic characteristics, a list of fruits and vegetables, and clinical manifestations of food allergy. Pollen allergy was diagnosed by skin prick test and/or measurement of the serum level of specific IgE. RESULTS: A total of 648 pollinosis patients were enrolled. The prevalence of PFAS was 41.7% (n = 270). PFAS patients exhibited cutaneous (43.0%), respiratory (20.0%), cardiovascular (3.7%) or neurologic symptoms (4.8%) in addition to oropharyngeal symptoms. Anaphylaxis was noted in 8.9% of the PFAS patients. Seventy types of foods were linked to PFAS; e.g., peach (48.5%), apple (46.7%), kiwi (30.4%), peanut (17.4%), plum (16.3%), chestnut (14.8%), pineapple (13.7%), walnut (14.1%), Korean melon (12.6%), tomato (11.9%), melon (11.5%) and apricot (10.7%). Korean foods such as taro/taro stem (8.9%), ginseong (8.2%), perilla leaf (4.4%), bellflower root (4.4%), crown daisy (3.0%), deodeok (3.3%), kudzu root (3.0%) and lotus root (2.6%) were also linked to PFAS. CONCLUSIONS: This was the first nationwide study of PFAS in Korea. The prevalence of PFAS was 41.7%, and 8.9% of the PFAS patients had anaphylaxis. These results will provide clinically useful information to physicians.
