Psychiatric Manifestation in Patients with Parkinson's Disease.
10.3346/jkms.2018.33.e300
- Author:
Ji Won HAN
1
;
Yebin D AHN
;
Won Seok KIM
;
Cheol Min SHIN
;
Seong Jin JEONG
;
Yoo Sung SONG
;
Yun Jung BAE
;
Jong Min KIM
Author Information
1. Department of Neuropsychiatry, Seoul National University Bundang Hospital, Seongnam, Korea.
- Publication Type:Review
- Keywords:
Parkinson's Disease;
Psychiatry;
Depression;
Psychosis;
Impulse Control Disorder;
Dementia
- MeSH:
Anhedonia;
Anxiety;
Apathy;
Compulsive Behavior;
Delusions;
Dementia;
Depression;
Dopaminergic Neurons;
Hallucinations;
Humans;
Institutionalization;
Neurodegenerative Diseases;
Parkinson Disease*;
Prevalence;
Psychotic Disorders;
Quality of Life;
Risk Factors;
Substantia Nigra
- From:Journal of Korean Medical Science
2018;33(47):e300-
- CountryRepublic of Korea
- Language:English
-
Abstract:
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life — and the need for institutionalization — is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.
