Serum Periostin Is Negatively Correlated With Exposure to Formaldehyde and Volatile Organic Compounds in Children.
10.4168/aair.2018.10.6.716
- Author:
Dong Keon YON
1
;
Jaewoo AN
;
Eun Kyo HA
;
Hye Mi JEE
;
Kenji IZUHARA
;
Junya ONO
;
Young Ho JUNG
;
Kyung Suk LEE
;
Youn Ho SHEEN
;
Heysung BAEK
;
Man Yong HAN
Author Information
1. Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea. drmesh@gmail.com
- Publication Type:Brief Communication
- Keywords:
Periostin;
volatile organic compounds;
formaldehyde;
children
- MeSH:
Adult;
Child*;
Cohort Studies;
Cross-Sectional Studies;
Epidemiologic Studies;
Formaldehyde*;
Gyeonggi-do;
Happiness;
Humans;
Inflammation;
Prospective Studies;
Smoke;
Tobacco;
Volatile Organic Compounds*;
Xylenes
- From:Allergy, Asthma & Immunology Research
2018;10(6):716-721
- CountryRepublic of Korea
- Language:English
-
Abstract:
Epidemiological studies have shown that exposure to tobacco smoke causing irritation and inflammation in the airways tends to reduce serum periostin concentrations in adults. We now investigate prospective cross-sectional study on 135 Korean students aged 7 years in the first grade who were participating in the Seongnam Atopy Project for Children's Happiness 2016 (SAP2016) cohort. To the best of our knowledge, this is the first study to show significant inverse correlations between serum periostin concentration and exposure to xylene and formaldehyde in children. Our findings suggested the need for caution in using the serum periostin level as a marker for allergic diseases, since exposure to volatile organic compounds and formaldehyde may confound the interpretation of these results.
