Seroepidemiology of Hepatitis Viruses and Hepatitis B Genotypes of Female Marriage Immigrants in Korea.
10.3349/ymj.2018.59.9.1072
- Author:
Jae Cheol KWON
1
;
Hye Young CHANG
;
Oh Young KWON
;
Ji Hoon PARK
;
In Soo OH
;
Hyung Joon KIM
;
Jun Hyung LEE
;
Ha Jung ROH
;
Hyun Woong LEE
Author Information
1. Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Hepatitis virus;
prevalence;
genotype;
marriage;
immigrants
- MeSH:
Academies and Institutes;
Asia;
Asia, Southeastern;
Biomarkers;
Cambodia;
China;
Emigrants and Immigrants*;
Female*;
Genotype*;
Hepatitis A;
Hepatitis B Surface Antigens;
Hepatitis B virus;
Hepatitis B*;
Hepatitis Viruses*;
Hepatitis*;
Humans;
Immunoglobulin G;
Japan;
Korea*;
Marriage*;
Mass Screening;
Philippines;
Prevalence;
Public Health;
Seroepidemiologic Studies;
Vaccination;
Vietnam
- From:Yonsei Medical Journal
2018;59(9):1072-1078
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: The Korean society has moved rapidly toward becoming a multicultural society. This study aimed to estimate the seroprevalence of hepatitis viruses and investigate hepatitis B virus (HBV) genotypic diversity in female marriage immigrants. MATERIALS AND METHODS: Screening program was conducted at support centers for multicultural families in 21 administrative districts in Korea between July 2011 and January 2017. A total of 963 female marriage immigrants were included in this study. Blood samples were tested for hepatitis viral markers and HBV genotype. RESULTS: Subjects' median age was 33 years (20–40 years), and they originated from nine countries including Vietnam (n=422, 43.8%), China (n=311, 32.3%), the Philippines (n=85, 8.8%), Cambodia (n=58, 6.0%), and Japan (n=39, 4.0%). About 30% (n=288) of subjects required hepatitis A vaccination. HBsAg positive rate was 5.4% (n=52). Positive HBsAg results were the highest in subjects from Southeast Asia (6.6%, n=38). Anti-HBs positive rate was 60.4% (n=582). About 34% (n=329) of subjects who were negative for anti-HBs and HBsAg required HBV vaccinations. Genotypes B and C were found in 54.6% (n=12) and 45.4% (n=10) of the 22 subjects with HBV, in whom genotypes were tested. Eight (0.8%) subjects were positive for anti-HCV. Positive anti-HCV results were the highest in subjects from Central Asia (7.9%, n=3). CONCLUSION: Testing for hepatitis viral marker (hepatitis A virus IgG and HBsAg/anti-HBs) is needed for female marriage immigrants. Especially, HBV genotype B is different from genotype C of Koreans. Therefore, interest and attention to vaccination programs for female marriage immigrants are necessary for both clinicians and public health institutes.
